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Antibody Product Overview
| ELK.No | ES10128 |
| Product name | RB40L rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 282808 |
| Human Swiss-Prot | P0C0E4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RB40L |
| Fields | |
| Gene name | RAB40AL RLGP |
| Protein name | Ras-related protein Rab-40A-like (Ras-like GTPase) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 90-170 |
| Specificity | RB40L Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 30kD |
| Background | This gene encodes a member of the Rab40 subfamily of Rab small GTP-binding proteins that contains a C-terminal suppressors of cytokine signaling box. Disruptions in this gene are associated with Duchenne muscular dystrophy. [provided by RefSeq, Apr 2010], |
| Function | domain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,tissue specificity:Expressed in brain, heart, skeletal muscle, kidney and liver. Highest expression in brain., |
| Subcellular location | Membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Mitochondrion . |
| Expression | Expressed in brain, lung, heart, skeletal muscle, kidney and liver. Highest expression in brain. Expressed in fetal brain and kidney. |
Additional Images
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Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10128-100
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