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Antibody Product Overview
| ELK.No | ES10507 |
| Product name | CCNG2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 901 |
| Human Swiss-Prot | Q16589 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CCNG2 |
| Fields | >>FoxO signaling pathway;>>p53 signaling pathway |
| Gene name | CCNG2 |
| Protein name | Cyclin-G2 |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O08918 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 20-100 |
| Specificity | CCNG2 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 37kD |
| Background | The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Expression levels increase through the cell cycle to peak in the mid/late-S phase and decrease during G2/M phase.,function:May play a role in growth regulation and in negative regulation of cell cycle progesssion.,induction:Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,tissue specificity:High levels in cerebellum, thymus, spleen and prostate. Low levels in skeletal muscle., |
| Subcellular location | Cytoplasm . |
| Expression | High levels in cerebellum, thymus, spleen and prostate. Low levels in skeletal muscle. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10507-50
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