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Antibody Product Overview
| ELK.No | ES10637 |
| Product name | CITE2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10370 |
| Human Swiss-Prot | Q99967 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CITE2 |
| Fields | >>Mitophagy - animal |
| Gene name | CITED2 MRG1 |
| Protein name | Cbp/p300-interacting transactivator 2 (MSG-related protein 1) (MRG-1) (P35srj) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O35740 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 190-270 |
| Specificity | CITE2 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 29kD |
| Background | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2(CITED2) Homo sapiens The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012], |
| Function | function:Interferes with the binding of transcription factors HIF-1a and STAT2 to p300/CBP.,induction:By hypoxia and deferoxamine.,similarity:Belongs to the CITED family.,subunit:Binds to the p300/CBP CH1 region., |
| Subcellular location | Nucleus . Colocalizes with EP300 in dot-like structures. |
| Expression | Pancreas, |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10637-50
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