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Antibody Product Overview
| ELK.No | ES10944 |
| Product name | MDGA1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 266727 |
| Human Swiss-Prot | Q8NFP4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MDGA1 |
| Fields | |
| Gene name | MDGA1 MAMDC3 |
| Protein name | MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q0PMG2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P85171 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | MDGA1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six Ig-like domains, a single fibronectin type III domain, a MAM domain and a C-terminal GPI-anchoring site. Studies in other mammals suggest this protein plays a role in cell adhesion, migration, and axon guidance and, in the developing brain, neuronal migration. In humans, this gene is associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2016], |
| Function | function:Required for radial migration of cortical neurons in the superficial layer of the neocortex.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 MAM domain.,similarity:Contains 6 Ig-like (immunoglobulin-like) domains.,subcellular location:Associated with lipid rafts.,subunit:Interacts heterophilically through its MAM domain with proteins in axon-rich regions and through its Ig-like domains with proteins in differentiating muscle.,tissue specificity:Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues., |
| Subcellular location | Cell membrane ; Lipid-anchor, GPI-anchor . Associated with lipid rafts. |
| Expression | Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues. |
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: AO-06-ES10944-50
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