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Antibody Product Overview
| ELK.No | ES10965 |
| Product name | TXND5 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 81567 |
| Human Swiss-Prot | Q8NBS9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TXND5 |
| Fields | >>Protein processing in endoplasmic reticulum |
| Gene name | TXNDC5 TLP46 UNQ364/PRO700 |
| Protein name | Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q91W90 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TXND5 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 47kD |
| Background | thioredoxin domain containing 5(TXNDC5) Homo sapiens This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010], |
| Function | function:Involved in the development of lysosome-related organelles, such as melanosomes and platelet-dense granules.,function:Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast.,similarity:Belongs to the Muted family.,similarity:Belongs to the protein disulfide isomerase family.,similarity:Contains 2 thioredoxin domains.,similarity:Contains 3 thioredoxin domains.,subunit:Interacts with pallidin. Interacts with dystrobrevin binding protein 1 and CNO/cappuccino (By similarity). Part of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)., |
| Subcellular location | Endoplasmic reticulum lumen . |
| Expression | Eye,Liver,Lymph,Lymph node,Ovary,PCR rescued clones,Retina,Spleen,Stomach, |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10965-50
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