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HSP 90 (Acetyl Lys435) rabbit pAb
AO-06-ES1105-50
Antibody Product Overview
| ELK.No | ES1105 |
| Product name | HSP 90 (Acetyl Lys435) rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | HSP90AA1; HSP90A; HSPC1; HSPCA; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3320 |
| Human Swiss-Prot | P07900 |
| Source | Rabbit |
| Isotype | IgG |
| Target | HSP 90 |
| Fields | >>Protein processing in endoplasmic reticulum;>>PI3K-Akt signaling pathway;>>Necroptosis;>>Antigen processing and presentation;>>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>Th17 cell differentiation;>>Progesterone-mediated oocyte maturation;>>Estrogen signaling pathway;>>Salmonella infection;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Prostate cancer;>>Lipid and atherosclerosis;>>Fluid shear stress and atherosclerosis |
| Gene name | HSP90AA1 |
| Protein name | Heat shock protein HSP 90-alpha |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 15519 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P07901 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 299331 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P82995 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized acetyl-peptide derived from the human HSP 90 around the acetylation site of K435. |
| Specificity | Acetyl-HSP 90 (K435) Polyclonal Antibody detects endogenous levels of HSP 90 protein only when acetylated at K435. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012], |
| Function | caution:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.,function:Molecular chaperone.,function:Molecular chaperone. Has ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with AHSA1, SMYD3 and TOM34. Interacts with FNIP1 and HSF1., |
| Subcellular location | Nucleus . Cytoplasm . Melanosome . Cell membrane . Mitochondrion . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Expression | Adult brain,Brain,Brain cortex,Breast,Cajal-Retzius |
Additional Images
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Western Blot analysis of A549 cells using Acetyl-HSP 90 (K435) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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Western Blot analysis of A549 cells using Acetyl-HSP 90 (K435) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
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