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Antibody Product Overview
| ELK.No | ES11060 |
| Product name | FHR1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3078 |
| Human Swiss-Prot | Q03591 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FHR1 |
| Fields | >>Complement and coagulation cascades |
| Gene name | CFHR1 CFHL CFHL1 CFHL1P CFHR1P FHR1 HFL1 HFL2 |
| Protein name | Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | FHR1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 36kD |
| Background | This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009], |
| Function | function:Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.,PTM:N-glycosylated. Two forms are observed; one with a single side chain and the other with two.,similarity:Contains 5 Sushi (CCP/SCR) domains.,tissue specificity:Expressed by the liver and secreted in plasma., |
| Subcellular location | Secreted. |
| Expression | Expressed by the liver and secreted in plasma. |
Additional Images
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Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11060-50
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