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Antibody Product Overview
| ELK.No | ES11108 |
| Product name | TEFF1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 100526694 |
| Human Swiss-Prot | Q8IYR6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TEFF1 |
| Fields | |
| Gene name | TMEFF1 C9orf2 |
| Protein name | Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q6PFE7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q9QYV1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TEFF1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | function:May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.,similarity:Belongs to the tomoregulin family.,similarity:Belongs to the UPF0439 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Kazal-like domains.,subunit:May interact with ST14.,tissue specificity:Expressed in brain.,tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues., |
| Function | function:May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.,similarity:Belongs to the tomoregulin family.,similarity:Belongs to the UPF0439 family.,similarity:Contains 1 EGF-like domain.,similarity:Contains 2 Kazal-like domains.,subunit:May interact with ST14.,tissue specificity:Expressed in brain.,tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . |
| Expression | Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11108-50
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