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Antibody Product Overview
| ELK.No | ES11146 |
| Product name | NINJ1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4814 |
| Human Swiss-Prot | Q92982 |
| Source | Rabbit |
| Isotype | IgG |
| Target | NINJ1 |
| Fields | |
| Gene name | NINJ1 |
| Protein name | Ninjurin-1 (Nerve injury-induced protein 1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O70131 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P70617 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein. AA range 1-56 |
| Specificity | NINJ1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 16kD |
| Background | The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009], |
| Function | function:Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations.,induction:By nerve injury both in dorsal root ganglion neurons and in Schwann cells.,similarity:Belongs to the ninjurin family.,tissue specificity:Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin., |
| Subcellular location | [Ninjurin-1]: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptic cell membrane ; Multi-pass membrane protein .; [Secreted ninjurin-1]: Secreted . |
| Expression | Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11146-50
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