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Antibody Product Overview
| ELK.No | ES11207 |
| Product name | VAMP1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6843 |
| Human Swiss-Prot | P23763 |
| Source | Rabbit |
| Isotype | IgG |
| Target | VAMP1 |
| Fields | >>SNARE interactions in vesicular transport |
| Gene name | VAMP1 SYB1 |
| Protein name | Vesicle-associated membrane protein 1 (VAMP-1) (Synaptobrevin-1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q62442 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q63666 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | VAMP1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 12kD |
| Background | Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014], |
| Function | function:Involved in the targeting and/or fusion of transport vesicles to their target membrane.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subunit:Interacts with VAPA and VAPB.,tissue specificity:Nervous system, skeletal muscle and adipose tissue., |
| Subcellular location | [Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 2]: Cytoplasmic vesicle membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome .; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein . |
| Expression | Nervous system, skeletal muscle and adipose tissue. |
Additional Images
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Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11207-100
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