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Antibody Product Overview
| ELK.No | ES11314 |
| Product name | PGS1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 633 |
| Human Swiss-Prot | P21810 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PGS1 |
| Fields | |
| Gene name | BGN SLRR1A |
| Protein name | Biglycan (Bone/cartilage proteoglycan I) (PG-S1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P28653 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P47853 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 110-190 |
| Specificity | PGS1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kD |
| Background | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015], |
| Function | function:May be involved in collagen fiber assembly.,PTM:The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class I subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Homodimer. Forms a ternary complex with MFAP2 and ELN.,tissue specificity:Found in several connective tissues, especially in articular cartilages., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . |
| Expression | Found in several connective tissues, especially in articular cartilages. |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11314-50
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