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Antibody Product Overview
| ELK.No | ES11480 |
| Product name | GPR78 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 27201 |
| Human Swiss-Prot | Q96P69 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GPR78 |
| Fields | |
| Gene name | GPR78 UNQ5925/PRO19818 |
| Protein name | G-protein coupled receptor 78 |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 290-370 |
| Specificity | GPR78 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 39kD |
| Background | The protein encoded by this gene belongs to the G protein-coupled receptor family, which contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. This is an orphan receptor, which displays significant level of constitutive activity. Association analysis shows preliminary evidence for the involvement of this gene in susceptibility to bipolar affective disorder and schizophrenia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011], |
| Function | function:Orphan receptor.,induction:Expression increased in fibroblasts or HeLa cells following UV-A irradiation, exposure to DNA-alkylating agents, or endoplasmic reticulum (ER) stress caused by osmotic shock or the glycosylation inhibitor tunicamycin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in pituitary and placenta. No expression detected in brain, skeletal muscle, lung, heart, liver, pancreas, or kidney., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11480-50
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