GPR33 rabbit pAb

GPR33 rabbit pAb

AO-06-ES11498-100

GPR33 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES11498
Product nameGPR33 rabbit pAb
ReactivityHuman;Rat;Mouse;
ApplicationsWB;ELISA
Other name
Size100μL
Unit price ($)248
Human gene ID2856
Human Swiss-ProtQ49SQ1
SourceRabbit
IsotypeIgG
TargetGPR33
Fields
Gene nameGPR33
Protein nameProbable G-protein coupled receptor 33
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtO88416
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityGPR33 Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)36kD
BackgroundThis gene has been identified as an orphan chemoattractant G-protein-coupled receptors (GPCR) pseudogene. Studies have shown that the inactivated gene is present as the predominant allele in the human population. A small fraction of the human population has been found to harbor an intact allele.[provided by RefSeq, Oct 2010],
Functionfunction:Orphan receptor; could be a chemoattractant receptor.,polymorphism:In most individuals a nonsense mutation transforms the Arg-140 into a premature stop codon. Out of 1217 individuals, 1166 had a stop codon in both alleles, 50 were heterozygous and only one (in the Philippines) had Arg-140 in both alleles. GPR33 has undergone independent pseudogenization in human, chimpanzee, orangutan, siamang and rat. This selective inactivation may be due to its interaction with a putative pathogen that could use GPR33 as a receptor for cell invasion.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in spleen, lung, heart, liver, kidney, pancreas, thymus, gonads and leukocytes.,
Subcellular locationCell membrane; Multi-pass membrane protein.
ExpressionExpressed in spleen, lung, heart, liver, kidney, pancreas, thymus, gonads and leukocytes.

Additional Images

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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11498-100
: 10 Produits
Hurry! only 10 items left in stock.

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