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Antibody Product Overview
| ELK.No | ES12200 |
| Product name | ZKSC1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 7586 |
| Human Swiss-Prot | P17029 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ZKSC1 |
| Fields | |
| Gene name | ZKSCAN1 KOX18 ZNF139 ZNF36 |
| Protein name | ZKSC1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74570 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BGS3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 498160 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4KLI1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human ZKSC1 AA range: 313-363 |
| Specificity | This antibody detects endogenous levels of ZKSC1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.112% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010], |
| Function | function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 1 SCAN box domain.,similarity:Contains 6 C2H2-type zinc fingers., |
| Subcellular location | Nucleus . |
| Expression | Brain,Epithelium,Eye,Fetal kidney,Insulinoma,Lung,Lymphoid,Pancreas,Spleen, |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12200-100
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