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Antibody Product Overview
| ELK.No | ES12215 |
| Product name | ZER1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10444 |
| Human Swiss-Prot | Q7Z7L7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ZER1 |
| Fields | |
| Gene name | ZER1 C9orf60 ZYG ZYG11BL |
| Protein name | ZER1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 227693 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80ZJ6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ZER1 AA range: 388-438 |
| Specificity | This antibody detects endogenous levels of ZER1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.318% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012], |
| Function | function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas., |
| Subcellular location | Cul2-RING ubiquitin ligase complex, |
| Expression | Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas. |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12215-100
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