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Antibody Product Overview
| ELK.No | ES12309 |
| Product name | WDR82 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 80335 |
| Human Swiss-Prot | Q6UXN9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | WDR82 |
| Fields | >>mRNA surveillance pathway |
| Gene name | WDR82 WDR82A UNQ9342/PRO34047 |
| Protein name | WDR82 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 77305 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BFQ4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human WDR82 AA range: 219-269 |
| Specificity | This antibody detects endogenous levels of WDR82 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 34kD |
| Observed band (KD) | |
| Background | TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010], |
| Function | caution:The gene encoding this protein shares one overlapping exon with TMEM113.,function:Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3.,similarity:Belongs to the WD repeat SWD2 family.,similarity:Contains 6 WD repeats.,subunit:Interacts with CUL4B. Component of the SET1 complex, at least composed of the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2/ASH2L and CXXC1/CFP1., |
| Subcellular location | Nucleus . Chromosome . Associates with chromatin (PubMed:20516061). Recruited at sites of high RNA polymerase II occupancy (By similarity). . |
| Expression |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12309-50
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