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Antibody Product Overview
| ELK.No | ES12371 |
| Product name | VGLU1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Vesicular glutamate transporter 1 (VGluT1) (Brain-specific Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 7) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 57030 |
| Human Swiss-Prot | Q9P2U7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | VGLU1 |
| Fields | >>Synaptic vesicle cycle;>>Retrograde endocannabinoid signaling;>>Glutamatergic synapse;>>Nicotine addiction |
| Gene name | SLC17A7 BNPI VGLUT1 |
| Protein name | VGLU1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72961 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3TXX4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 116638 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q62634 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human VGLU1 AA range: 488-538 |
| Specificity | This antibody detects endogenous levels of VGLU1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.79% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008], |
| Function | function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe., |
| Subcellular location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome . |
| Expression | Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe. |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12371-100
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