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Antibody Product Overview
| ELK.No | ES12418 |
| Product name | UPP2 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 151531 |
| Human Swiss-Prot | O95045 |
| Source | Rabbit |
| Isotype | IgG |
| Target | UPP2 |
| Fields | >>Pyrimidine metabolism;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Nucleotide metabolism |
| Gene name | UPP2 |
| Protein name | UPP2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 76654 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CGR7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human UPP2 AA range: 164-214 |
| Specificity | This antibody detects endogenous levels of UPP2 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 35kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.,function:Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.,pathway:Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.,similarity:Belongs to the PNP/UDP phosphorylase family.,tissue specificity:Predominantly expressed in kidney., |
| Subcellular location | cytoplasm,cytosol,type III intermediate filament, |
| Expression | Predominantly expressed in kidney. |
Additional Images
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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12418-50
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