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Antibody Product Overview
| ELK.No | ES12463 |
| Product name | U119A rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9094 |
| Human Swiss-Prot | Q13432 |
| Source | Rabbit |
| Isotype | IgG |
| Target | U119A |
| Fields | |
| Gene name | UNC119 RG4 |
| Protein name | U119A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22248 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z2R6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29402 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q62885 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human U119A AA range: 153-203 |
| Specificity | This antibody detects endogenous levels of U119A at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 26kD |
| Observed band (KD) | |
| Background | This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008], |
| Function | function:May play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle.,similarity:Belongs to the PDE6D/unc-119 family.,tissue specificity:Retinal-specific. Localized in photoreceptor synapses in the outer plexiform layer of the retina., |
| Subcellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, spindle . Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells. . |
| Expression | Abundantly expressed in retina, in photoreceptor synapses and inner segments. Expressed in a much lesser extent in several other tissues. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12463-50
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