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Antibody Product Overview
| ELK.No | ES12480 |
| Product name | TXND8 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 255220 |
| Human Swiss-Prot | Q6A555 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TXND8 |
| Fields | |
| Gene name | TXNDC8 SPTRX3 TRX6 |
| Protein name | TXND8 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67402 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q69AB2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 362525 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q69AB1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TXND8 AA range: 64-114 |
| Specificity | This antibody detects endogenous levels of TXND8 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 14kD |
| Observed band (KD) | |
| Background | |
| Function | function:May be required for post-translational modifications of proteins required for acrosomal biogenesis. May act by reducing disulfide bonds within the sperm.,miscellaneous:Increased levels, possibly caused by overexpression, are observed in morphologically abnormal spermatozoa from infertile men, suggesting that it may be used as a marker of aberrant spermatogenesis.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,tissue specificity:Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level)., |
| Subcellular location | Cytoplasm . Golgi apparatus . |
| Expression | Testis-specific. Only expressed during spermiogenesis, prominently in the Golgi apparatus of pachytene spermatocytes and round and elongated spermatids, with a transient localization in the developing acrosome of round spermatids (at protein level). |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12480-50
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