TSG10 rabbit pAb

TSG10 rabbit pAb

AO-06-ES12537-50

TSG10 rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES12537
Product nameTSG10 rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB
Other name
Size50μL
Unit price ($)148
Human gene ID80705
Human Swiss-ProtQ9BZW7
SourceRabbit
IsotypeIgG
TargetTSG10
Fields
Gene nameTSGA10 CEP4L
Protein nameTSG10
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID211484
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ6NY15
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID252923
Rat gene linkView Rat Gene
Rat Swiss-ProtQ9Z220
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human TSG10 AA range: 412-462
SpecificityThis antibody detects endogenous levels of TSG10 at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)77kD
Observed band (KD)
Background
Functionfunction:May play a role in the sperm tail fibrous sheath, a major sperm tail structure.,PTM:Appears to be processed in a 27 kDa and a 55 kDa peptide containing respectively the N-terminal and the C-terminal part of the precursor.,similarity:Belongs to the CEP135/TSGA10 family.,subcellular location:The 27 kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail while the 55 kDa peptide localizes to the midpiece.,tissue specificity:Testis specific.,
Subcellular locationCytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). .
ExpressionExpressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816).

Additional Images

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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12537-50
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Hurry! only 10 items left in stock.

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