Français
English
Antibody Product Overview
| ELK.No | ES12554 |
| Product name | TRM6 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51605 |
| Human Swiss-Prot | Q9UJA5 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRM6 |
| Fields | |
| Gene name | TRMT6 KIAA1153 TRM6 CGI-09 |
| Protein name | TRM6 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66926 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CE96 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human TRM6 AA range: 175-225 |
| Specificity | This antibody detects endogenous levels of TRM6 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 55kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | function:Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TRM6/GCD10 family.,subunit:tRNA (adenine-N(1)-)-methyltransferase is a heterodimer of trm6 and trm61.,tissue specificity:Expressed in brain, liver, testis and ovary., |
| Subcellular location | Nucleus . |
| Expression | Expressed in brain, liver, testis and ovary. |
Additional Images
No image
Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES12554-50
: 10 Produits
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package