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Antibody Product Overview
| ELK.No | ES12564 |
| Product name | TRIM2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 23321 |
| Human Swiss-Prot | Q9C040 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRIM2 |
| Fields | |
| Gene name | TRIM2 KIAA0517 RNF86 |
| Protein name | TRIM2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 80890 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9ESN6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 361970 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | D3ZQG6 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TRIM2 AA range: 162-212 |
| Specificity | This antibody detects endogenous levels of TRIM2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 82kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014], |
| Function | domain:The interaction with myosin V is dependent upon its NHL repeats, which form a beta-propeller (NHL) domain containing six blades.,function:May contribute to the alteration of neural cellular mechanisms.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 filamin repeat.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 6 NHL repeats.,subunit:Interacts with myosin V., |
| Subcellular location | Cytoplasm . |
| Expression |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12564-50
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