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Antibody Product Overview
| ELK.No | ES12820 |
| Product name | TALDO rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6888 |
| Human Swiss-Prot | P37837 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TALDO |
| Fields | >>Pentose phosphate pathway;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids |
| Gene name | TALDO1 TAL TALDO TALDOR |
| Protein name | TALDO |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 21351 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q93092 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 83688 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9EQS0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TALDO AA range: 21-71 |
| Specificity | This antibody detects endogenous levels of TALDO at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 37kD |
| Observed band (KD) | |
| Background | Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.,disease:Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.,function:Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.,similarity:Belongs to the transaldolase family.,similarity:Belongs to the transaldolase family. Type 1 subfamily., |
| Subcellular location | Cytoplasm . |
| Expression |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12820-50
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