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Antibody Product Overview
| ELK.No | ES12834 |
| Product name | T3HPD rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) (Trans-3-hydroxy-l-proline dehydratase) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 112849 |
| Human Swiss-Prot | Q96EM0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | T3HPD |
| Fields | >>Arginine and proline metabolism;>>Metabolic pathways |
| Gene name | L3HYPDH C14orf149 |
| Protein name | T3HPD |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67217 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CXA2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human T3HPD AA range: 11-61 |
| Specificity | This antibody detects endogenous levels of T3HPD at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.62% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016], |
| Function | catalytic activity:L-proline = D-proline.,function:Catalyzes the interconversion of L- and D-proline.,miscellaneous:In contrast to the T.cruzi enzyme, lacks the conserved Cys at position 273 which is replaced by a Thr residue. The high conservation of the protein nevertheless suggests that it is nevertheless active.,similarity:Belongs to the proline racemase family.,subunit:Homodimer., |
| Subcellular location | |
| Expression | Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12834-100
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