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Antibody Product Overview
| ELK.No | ES12851 |
| Product name | SYTL1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 84958 |
| Human Swiss-Prot | Q8IYJ3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SYTL1 |
| Fields | |
| Gene name | SYTL1 SLP1 SB146 |
| Protein name | SYTL1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q99N80 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SYTL1 AA range: 333-383 |
| Specificity | This antibody detects endogenous levels of SYTL1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.101% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | |
| Function | function:May act as Rab effector protein and play a role in vesicle trafficking (By similarity). Binds phosphatidylinositol 3,4,5-triphosphate.,similarity:Contains 1 C2 domain.,similarity:Contains 1 RabBD (Rab-binding) domain.,similarity:Contains 2 C2 domains.,subcellular location:Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes.,subunit:Monomer. Binds NRXN1. Binds RAB27A that has been activated by GTP-binding via its N-terminus (By similarity). Binds NCF2.,tissue specificity:Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea., |
| Subcellular location | Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Peripheral membrane protein tightly bound to the cytoplasmic side of cellular membranes. |
| Expression | Highly expressed in bone marrow and lymphoid tissues. Detected at lower levels in cerebellum, occipital lobe, prostate, stomach, kidney, appendix, lung and trachea. Expressed in cytotoxic T-lymphocytes (CTL). |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12851-100
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