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Antibody Product Overview
| ELK.No | ES12869 |
| Product name | SYCM rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Probable cysteine--tRNA ligase, mitochondrial (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 79587 |
| Human Swiss-Prot | Q9HA77 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SYCM |
| Fields | >>Aminoacyl-tRNA biosynthesis |
| Gene name | CARS2 OK/SW-cl.10 |
| Protein name | SYCM |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 71941 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BYM8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SYCM AA range: 95-145 |
| Specificity | This antibody detects endogenous levels of SYCM at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.121% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of cysteine to tRNA molecules. A splice-site mutation in this gene has been associated with a novel progressive myoclonic epilepsy disease with similar symptoms to MERRF syndrome. [provided by RefSeq, Mar 2015], |
| Function | catalytic activity:ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the class-I aminoacyl-tRNA synthetase family., |
| Subcellular location | Mitochondrion matrix . |
| Expression | Colon adenocarcinoma,Lung,Lymph node,Mammary gland,Salivary gland,Testis, |
Additional Images
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Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12869-100
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