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Antibody Product Overview
| ELK.No | ES12888 |
| Product name | STX5 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Syntaxin-5 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6811 |
| Human Swiss-Prot | Q13190 |
| Source | Rabbit |
| Isotype | IgG |
| Target | STX5 |
| Fields | >>SNARE interactions in vesicular transport |
| Gene name | STX5 STX5A |
| Protein name | STX5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56389 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K1E0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 65134 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q08851 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human STX5 AA range: 233-283 |
| Specificity | This antibody detects endogenous levels of STX5 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.74% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This gene encodes a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for v-SNAREs (vesicle-SNAP receptors), permitting specific synaptic vesicle docking and fusion. The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy. Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011], |
| Function | function:Mediates endoplasmic reticulum to Golgi transport (By similarity). Golgi apparatus membrane; Single-pass type IV membrane protein .,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain.,subunit:Part of a ternary complex containing STX5A, NSFL1C and VCP. Identified in a unique SNARE complex composed of the Golgi SNAREs GOSR1, GOSR2 and YKT6., |
| Subcellular location | Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type IV membrane protein . Golgi apparatus membrane . Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. . |
| Expression | B-cell,Heart,Kidney,Umbilical cord blood,Uterus, |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12888-50
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