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Antibody Product Overview
| ELK.No | ES12889 |
| Product name | STX3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6809 |
| Human Swiss-Prot | Q13277 |
| Source | Rabbit |
| Isotype | IgG |
| Target | STX3 |
| Fields | >>SNARE interactions in vesicular transport;>>Synaptic vesicle cycle |
| Gene name | STX3 STX3A |
| Protein name | STX3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20908 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q64704 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 81802 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q08849 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human STX3 AA range: 6-56 |
| Specificity | This antibody detects endogenous levels of STX3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 32kD |
| Observed band (KD) | |
| Background | The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010], |
| Function | function:Potentially involved in docking of synaptic vesicles at presynaptic active zones.,similarity:Belongs to the syntaxin family.,similarity:Contains 1 t-SNARE coiled-coil homology domain., |
| Subcellular location | [Isoform A]: Apical cell membrane ; Single-pass type IV membrane protein . Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors. .; [Isoform 3]: Nucleus . |
| Expression | [Isoform A]: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. ; [Isoform B]: Expressed only in the retina. ; [Isoform 3]: Ubiquitously expressed. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12889-100
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