SNX17 rabbit pAb

SNX17 rabbit pAb

AO-06-ES13031-100

SNX17 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES13031
Product nameSNX17 rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB;IHC
Other name
Size100μL
Unit price ($)248
Human gene ID9784
Human Swiss-ProtQ15036
SourceRabbit
IsotypeIgG
TargetSNX17
Fields
Gene nameSNX17 KIAA0064
Protein nameSNX17
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID266781
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ8BVL3
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID298836
Rat gene linkView Rat Gene
Rat Swiss-ProtQ6AYS6
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human SNX17 AA range: 398-448
SpecificityThis antibody detects endogenous levels of SNX17 at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)52kD
Observed band (KD)
BackgroundThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],
Functiondomain:The PX domain is required for association with endosomes.,function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8.,
Subcellular locationCytoplasm . Early endosome . Cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side .
Expression

Additional Images

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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13031-100
: 10 Produits
Hurry! only 10 items left in stock.

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