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Antibody Product Overview
| ELK.No | ES13032 |
| Product name | SNX13 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 23161 |
| Human Swiss-Prot | Q9Y5W8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SNX13 |
| Fields | |
| Gene name | SNX13 KIAA0713 |
| Protein name | SNX13 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 217463 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6PHS6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SNX13 AA range: 602-652 |
| Specificity | This antibody detects endogenous levels of SNX13 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.277% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008], |
| Function | function:May be involved in several stages of intracellular trafficking. Act as a GAP for Galphas.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 PXA domain.,similarity:Contains 1 RGS domain., |
| Subcellular location | Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . |
| Expression | Amygdala,Brain,Placenta,Testis, |
Additional Images
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Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13032-50
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