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Antibody Product Overview
| ELK.No | ES13131 |
| Product name | SGPP1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 81537 |
| Human Swiss-Prot | Q9BX95 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SGPP1 |
| Fields | >>Sphingolipid metabolism;>>Metabolic pathways;>>Sphingolipid signaling pathway |
| Gene name | SGPP1 |
| Protein name | SGPP1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 81535 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JI99 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q99P55 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SGPP1 AA range: 47-97 |
| Specificity | This antibody detects endogenous levels of SGPP1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 49kD |
| Observed band (KD) | |
| Background | Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009], |
| Function | function:Has enzymatic activity against both sphingosine 1 phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels.,similarity:Belongs to the type 2 lipid phosphate phosphatase family.,tissue specificity:Ubiquitous, with the strongest level in placenta and kidney., |
| Subcellular location | Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . |
| Expression | Ubiquitous, with the strongest level in placenta and kidney. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13131-100
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