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Antibody Product Overview
| ELK.No | ES13139 |
| Product name | SG196 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 84197 |
| Human Swiss-Prot | Q9H5K3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SG196 |
| Fields | >>Mannose type O-glycan biosynthesis;>>Metabolic pathways |
| Gene name | SGK196 |
| Protein name | SG196 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74653 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3TUA9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 306549 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4V8A9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SG196 AA range: 178-228 |
| Specificity | This antibody detects endogenous levels of SG196 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 39kD |
| Observed band (KD) | |
| Background | This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013], |
| Function | domain:The protein kinase domain is predicted to be catalytically inactive.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.,similarity:Contains 1 protein kinase domain., |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein . |
| Expression | Highest expression is observed in brain, skeletal muscle, kidney and heart in fetal and adult tissues. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13139-50
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