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Antibody Product Overview
| ELK.No | ES13160 |
| Product name | SEM4F rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Semaphorin-4F (Semaphorin-M) (Sema M) (Semaphorin-W) (Sema W) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10505 |
| Human Swiss-Prot | O95754 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SEM4F |
| Fields | >>Axon guidance |
| Gene name | SEMA4F SEMAM SEMAW |
| Protein name | SEM4F |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20355 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z123 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 29745 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9Z143 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SEM4F AA range: 85-135 |
| Specificity | This antibody detects endogenous levels of SEM4F at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.336% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012], |
| Function | function:Has growth cone collapse activity against retinal ganglion-cell axons.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain., |
| Subcellular location | Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, dendrite . Colocalizes with DLG4 at synapses. . |
| Expression | Amygdala,Brain,Liver, |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13160-100
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