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Antibody Product Overview
| ELK.No | ES13175 |
| Product name | SDHL rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10993 |
| Human Swiss-Prot | P20132 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SDHL |
| Fields | >>Glycine, serine and threonine metabolism;>>Cysteine and methionine metabolism;>>Valine, leucine and isoleucine biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids |
| Gene name | SDS SDH |
| Protein name | SDHL |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 231691 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8VBT2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25044 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P09367 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SDHL AA range: 207-257 |
| Specificity | This antibody detects endogenous levels of SDHL at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 36kD |
| Observed band (KD) | |
| Background | This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:L-serine = pyruvate + NH(3).,cofactor:Pyridoxal phosphate.,pathway:Carbohydrate biosynthesis; gluconeogenesis.,similarity:Belongs to the serine/threonine dehydratase family.,subunit:Homodimer., |
| Subcellular location | Cytoplasm. |
| Expression |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13175-50
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