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Antibody Product Overview
| ELK.No | ES13177 |
| Product name | SDC3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 9672 |
| Human Swiss-Prot | O75056 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SDC3 |
| Fields | >>Cell adhesion molecules |
| Gene name | SDC3 KIAA0468 |
| Protein name | SDC3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20970 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q64519 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 116673 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P33671 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SDC3 AA range: 131-181 |
| Specificity | This antibody detects endogenous levels of SDC3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 49kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009], |
| Function | function:Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.,PTM:O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules.,similarity:Belongs to the syndecan proteoglycan family.,tissue specificity:Expressed in the nervous system, the adrenal gland, and the spleen., |
| Subcellular location | Cell membrane; Single-pass type I membrane protein. |
| Expression | Expressed in the nervous system, the adrenal gland, and the spleen. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13177-50
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