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Antibody Product Overview
| ELK.No | ES13220 |
| Product name | S7A14 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Probable cationic amino acid transporter (Solute carrier family 7 member 14) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 57709 |
| Human Swiss-Prot | Q8TBB6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | S7A14 |
| Fields | |
| Gene name | SLC7A14 KIAA1613 |
| Protein name | S7A14 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 241919 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BXR1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human S7A14 AA range: 50-100 |
| Specificity | This antibody detects endogenous levels of S7A14 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.341% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014], |
| Function | sequence caution:Translated as Glu.,similarity:Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family., |
| Subcellular location | Lysosome membrane ; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes. |
| Expression | Expressed in skin fibroblasts. |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13220-100
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