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Antibody Product Overview
| ELK.No | ES13226 |
| Product name | S47A1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Multidrug and toxin extrusion protein 1 (MATE-1) (hMATE-1) (Solute carrier family 47 member 1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 55244 |
| Human Swiss-Prot | Q96FL8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | S47A1 |
| Fields | |
| Gene name | SLC47A1 MATE1 |
| Protein name | S47A1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67473 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8K0H1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 360539 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5I0E9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human S47A1 AA range: 158-208 |
| Specificity | This antibody detects endogenous levels of S47A1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.186% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 65kD |
| Background | This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008], |
| Function | function:Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.,similarity:Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.,subcellular location:Predominantly localized at the plasma membrane but also found in intracellular organelles.,tissue specificity:Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membr |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . Predominantly localized at the plasma membrane but also found in intracellular organelles. |
| Expression | Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes). |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13226-100
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