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Antibody Product Overview
| ELK.No | ES13251 |
| Product name | S2610 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Solute carrier family 26 member 10 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 65012 |
| Human Swiss-Prot | Q8NG04 |
| Source | Rabbit |
| Isotype | IgG |
| Target | S2610 |
| Fields | |
| Gene name | SLC26A10 |
| Protein name | S2610 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q5EBI0 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human S2610 AA range: 295-345 |
| Specificity | This antibody detects endogenous levels of S2610 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.111% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | |
| Function | caution:According to PubMed:12759755, it is a transcribed pseudogene. They however do not provide experimental evidences to support this affirmation.,domain:The guanine nucleotide exchange activity is autoinhibited by the PH domain.,function:Chloride/bicarbonate exchanger.,function:May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis.,similarity:Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain |
| Subcellular location | Membrane ; Multi-pass membrane protein . |
| Expression | Brain,Cerebellum,Testis, |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13251-50
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