RDH14 rabbit pAb

RDH14 rabbit pAb

AO-06-ES13431-100

RDH14 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES13431
Product nameRDH14 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB;ELISA;IHC
Other name
Size100μL
Unit price ($)248
Human gene ID57665
Human Swiss-ProtQ9HBH5
SourceRabbit
IsotypeIgG
TargetRDH14
Fields
Gene nameRDH14 PAN2 UNQ529/PRO1072
Protein nameRDH14
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID105014
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9ERI6
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human RDH14 AA range: 283-333
SpecificityThis antibody detects endogenous levels of RDH14 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)37kD
Observed band (KD)
Background
Functioncatalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.,function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.,similarity:Belongs to the 5'-nucleotidase type 3 family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,tissue specificity:Expressed in brain, kidney, pancreas and placenta.,tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.,
Subcellular locationnucleus,mitochondrion,lysosomal membrane,endoplasmic reticulum,endoplasmic reticulum membrane,membrane,
ExpressionWidely expressed.

Additional Images

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Western blot analysis of lysates from MDA-MB cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13431-100
: 10 Produits
Hurry! only 10 items left in stock.

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