RABEK rabbit pAb

RABEK rabbit pAb

AO-06-ES13480-50

RABEK rabbit pAb 50μL

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299,00 €
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Antibody Product Overview

ELK.NoES13480
Product nameRABEK rabbit pAb
ReactivityHuman; Mouse;Rat
ApplicationsWB;ELISA;IHC
Other name
Size50μL
Unit price ($)148
Human gene ID10244
Human Swiss-ProtQ7Z6M1
SourceRabbit
IsotypeIgG
TargetRABEK
Fields
Gene nameRABEPK RAB9P40
Protein nameRABEK
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID227746
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ8VCH5
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID296649
Rat gene linkView Rat Gene
Rat Swiss-ProtQ4V8F4
Rat Swiss linkView Rat Swiss-Prot
ImmunogenSynthesized peptide derived from human RABEK AA range: 227-277
SpecificityThis antibody detects endogenous levels of RABEK at Human/Mouse/Rat
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)41kD
Observed band (KD)
Background
Functionfunction:Rab9 effector required for endosome to trans-Golgi network (TGN) transport.,PTM:Phosphorylated on Ser residues most probably by PIP5K3.,similarity:Contains 5 Kelch repeats.,subcellular location:Interaction with PIP5K3 and subsequent phosphorylation recruits it to the endosomal membrane.,subunit:Interacts with PIP5K3. Interacts with RAB9 in its GTP-bound conformation.,
Subcellular locationCytoplasm. Endosome membrane . Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane. .
Expression

Additional Images

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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13480-50
: 10 Produits
Hurry! only 10 items left in stock.

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