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Antibody Product Overview
| ELK.No | ES13821 |
| Product name | RAB3A rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 5864 |
| Human Swiss-Prot | P20336 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RAB3A |
| Fields | >>Synaptic vesicle cycle;>>Insulin secretion |
| Gene name | RAB3A |
| Protein name | RAB3A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 19339 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P63011 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25531 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P63012 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human RAB3A AA range: 27-77 |
| Specificity | This antibody detects endogenous levels of RAB3A at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 24kD |
| Observed band (KD) | |
| Background | |
| Function | function:Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3.,tissue specificity:Specifically expressed in brain., |
| Subcellular location | Cytoplasm, cytosol . Lysosome . Cytoplasmic vesicle, secretory vesicle . Cell projection, axon . Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cycles between a vesicle-associated GTP-bound form and a cytosolic GDP-bound form. . |
| Expression | Specifically expressed in brain. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13821-100
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