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Antibody Product Overview
| ELK.No | ES13875 |
| Product name | PTBP3 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9991 |
| Human Swiss-Prot | O95758 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PTBP3 |
| Fields | |
| Gene name | PTBP3 ROD1 |
| Protein name | PTBP3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 230257 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BHD7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 83515 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q9Z118 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PTBP3 AA range: 103-153 |
| Specificity | This antibody detects endogenous levels of PTBP3 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 61kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011], |
| Function | function:May play a role in regulation of differentiation. In vitro, binds RNA, preferentially to both poly(G) and poly(U). Overexpressed, blocks differentiation of K562 leukemia cells following treatment with phorbol esters or sodium butyrate without affecting proliferation.,similarity:Contains 4 RRM (RNA recognition motif) domains.,tissue specificity:Expressed in several hematopoietic cell lines examined., |
| Subcellular location | nucleus, |
| Expression | Expressed in several hematopoietic cell lines examined. |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13875-100
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