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Antibody Product Overview
| ELK.No | ES13964 |
| Product name | PRD14 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 63978 |
| Human Swiss-Prot | Q9GZV8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PRD14 |
| Fields | |
| Gene name | PRDM14 |
| Protein name | PRD14 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 383491 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | E9Q3T6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PRD14 AA range: 391-441 |
| Specificity | This antibody detects endogenous levels of PRD14 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 63kD |
| Observed band (KD) | |
| Background | This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011], |
| Function | function:May be involved in transcriptional regulation.,similarity:Contains 1 SET domain.,similarity:Contains 6 C2H2-type zinc fingers., |
| Subcellular location | Nucleus . |
| Expression | Expressed in embryonic stem cells. Tends to be overexpressed in breast cancer (at protein level). |
Additional Images
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Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13964-100
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