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Antibody Product Overview
| ELK.No | ES14045 |
| Product name | PNMA1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Paraneoplastic antigen Ma1 (37 kDa neuronal protein) (Neuron- and testis-specific protein 1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9240 |
| Human Swiss-Prot | Q8ND90 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PNMA1 |
| Fields | |
| Gene name | PNMA1 MA1 |
| Protein name | PNMA1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 70481 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8C1C8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 170636 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8VHZ4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PNMA1 AA range: 14-64 |
| Specificity | This antibody detects endogenous levels of PNMA1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.39% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This gene encodes a neuron- and testis-specific protein that is also expressed in some paraneoplastic syndromes affecting the nervous system. Some patients with neurologic disorders develop antibodies against the protein encoded by this gene. The identification of the antineuronal antibodies in the sera of these patients has facilitated the diagnosis of paraneoplastic neurological disorders and the early detection of the associated tumors. [provided by RefSeq, Feb 2014], |
| Function | miscellaneous:Antibodies against PNMA1 are present in sera from patients suffering of paraneoplastic neurological disorders.,similarity:Belongs to the PNMA family.,subcellular location:In tumor cells, it is cytoplasmic.,tissue specificity:Testis and brain specific. In some patients suffering from cancers, it is also specifically expressed by the paraneoplastic tumor cells., |
| Subcellular location | Nucleus, nucleolus . In tumor cells, it is cytoplasmic. |
| Expression | Testis- and brain-specific. In some cancer patients, specifically expressed by paraneoplastic tumor cells. |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14045-100
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