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Antibody Product Overview
| ELK.No | ES14062 |
| Product name | PLP2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 5355 |
| Human Swiss-Prot | Q04941 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PLP2 |
| Fields | |
| Gene name | PLP2 A4 |
| Protein name | PLP2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18824 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9R1Q7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 302562 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q6P742 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PLP2 AA range: 56-106 |
| Specificity | This antibody detects endogenous levels of PLP2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 17kD |
| Observed band (KD) | |
| Background | This gene encodes an integral membrane protein that localizes to the endoplasmic reticulum in colonic epithelial cells. The encoded protein can multimerize and may function as an ion channel. A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Jan 2010], |
| Function | function:May play a role in cell differentiation in the intestinal epithelium.,similarity:Contains 1 MARVEL domain.,tissue specificity:Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14062-100
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