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Antibody Product Overview
| ELK.No | ES14065 |
| Product name | PLEK2 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Pleckstrin-2 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 26499 |
| Human Swiss-Prot | Q9NYT0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PLEK2 |
| Fields | |
| Gene name | PLEK2 |
| Protein name | PLEK2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 27260 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9WV52 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PLEK2 AA range: 5-55 |
| Specificity | This antibody detects endogenous levels of PLEK2 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.38% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015], |
| Function | function:May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.,similarity:Contains 1 DEP domain.,similarity:Contains 2 PH domains., |
| Subcellular location | Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. |
| Expression | Cervix,Ovary, |
Additional Images
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Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14065-100
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