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Antibody Product Overview
| ELK.No | ES14135 |
| Product name | PHLP2 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 23035 |
| Human Swiss-Prot | Q6ZVD8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PHLP2 |
| Fields | >>PI3K-Akt signaling pathway |
| Gene name | PHLPP2 KIAA0931 PHLPPL |
| Protein name | PHLP2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 244650 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BXA7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PHLP2 AA range: 381-431 |
| Specificity | This antibody detects endogenous levels of PHLP2 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 146kD |
| Observed band (KD) | |
| Background | |
| Function | |
| Subcellular location | Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus. |
| Expression | In colorectal cancer tissue, expression is highest in the surface epithelium of normal colonic mucosa adjacent to the cancer tissue but is largely excluded from the crypt bases. Expression is lost or significantly decreased in 80% of tested tumors (at protein level). |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14135-50
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