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Antibody Product Overview
| ELK.No | ES14167 |
| Product name | PEF1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 553115 |
| Human Swiss-Prot | Q9UBV8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PEF1 |
| Fields | |
| Gene name | PEF1 ABP32 UNQ1845/PRO3573 |
| Protein name | PEF1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 67898 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BFY6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 297900 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q641Z8 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PEF1 AA range: 109-159 |
| Specificity | This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 31kD |
| Observed band (KD) | |
| Background | This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010], |
| Function | similarity:Contains 5 EF-hand domains.,subcellular location:Membrane-associated in the presence of Ca(2+).,subunit:Heterodimer; heterodimerizes with PDCD6/ALG2. Dissociates from PDCD6/ALG2 in presence of Ca(2+)., |
| Subcellular location | Cytoplasm . Endoplasmic reticulum . Membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein . Membrane-associated in the presence of Ca(2+) (PubMed:11278427). Localizes to endoplasmic reticulum exit site (ERES) (By similarity). . |
| Expression |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES14167-50
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