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Antibody Product Overview
| ELK.No | ES14272 |
| Product name | PANK4 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Pantothenate kinase 4 (hPanK4) (EC 2.7.1.33) (Pantothenic acid kinase 4) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 55229 |
| Human Swiss-Prot | Q9NVE7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PANK4 |
| Fields | |
| Gene name | PANK4 |
| Protein name | PANK4 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 269614 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q80YV4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 171053 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q923S8 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PANK4 AA range: 8-58 |
| Specificity | This antibody detects endogenous levels of PANK4 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.351% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is most abundant in muscle but is expressed in all tissues. [provided by RefSeq, Jul 2008], |
| Function | catalytic activity:ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.,enzyme regulation:Regulated by feedback inhibition by CoA and its thioesters.,function:Plays a role in the physiological regulation of the intracellular CoA concentration.,pathway:Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 1/5.,similarity:Belongs to the type II pantothenate kinase family.,subunit:Interacts with PKM2.,tissue specificity:Ubiquitously expressed with higher expression in the muscle., |
| Subcellular location | Cytoplasm . |
| Expression | Ubiquitously expressed with higher expression in the muscle. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14272-50
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